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But we know much more about addiction today and the effects of drugs and alcohol on the brain. People don’t choose to stay addicted to a substance—their brain demands the substance and more of it over time. Addiction is a brain disease, and here is how drugs and alcohol change the brain. The brain reacts to pleasure by releasing dopamine into the area of the brain known as the “pleasure center.” (This is technically called the nucleus accumbens .) Addictive substances give the pleasure center big-time rewards—lots of dopamine that immediately satisfy and create a surge of dopamine. Basically, addictive substances short-cut the brain’s pleasure system and make pleasure happen faster and more intensely. The brain gets strong signals and remembers those signals. (This leads us to the learning aspect of addiction.) So, how do we go from liking something to becoming addicted? The brain plays a role in that, too. While dopamine is flooding the pleasure center of the brain, giving us fast rewards for using an addictive substance, that dopamine is also teaching the brain to keep wanting the drug. Dopamine interacts with a neurotransmitter in the brain’s reward-learning system. This is the same system that makes us seek out things that help us survive, such as water. We hunt for it because our brain tells us we need it. Using addictive substances can teach the brain to go after the substance—to find it and use it. The brain tries to protect us, too, by releasing less dopamine over time. The more we use an addictive substance, the more we must use to get the same effect. The brain is trying to protect itself by muffling the effects of the drug—the fast pleasure, the feeling. But, because we are driven to get that reward, and we have learned to seek it, we take more of the drug or use more alcohol to achieve pleasure. Our tolerance to the addictive substance grows. Addiction makes us crave the drug and do whatever it takes to find and use it. Anyone can become addicted to drugs and alcohol. Addiction does not discriminate: men and women of all ages and races can develop an addiction. However, some people are more predisposed to addiction than others because of genetics or environmental factors.https://www.beachway.com/how-do-drugs-affect-the-brain/
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